Product Information
| Catalogue Number | 0763-E-AB-F1181D-01 |
| Product Size | 50 Tests |
| Clone | G8.8 |
| Clonality | Monoclonal |
| Conjugation | PE (Phycoerythrin) |
| Host | Rat |
| Reactivity | Mouse |
| Application | FCM |
| Dry Ice | No |
| Hazardous | No |
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product Description
The PE Anti-Mouse CD326/EpCAM Antibody [G8.8] is a rat monoclonal antibody designed to recognize mouse epithelial cell adhesion molecule (EpCAM), also known as CD326.
Conjugated to phycoerythrin (PE), this antibody enables fluorescent detection of EpCAM-expressing cells by flow cytometry (FCM). It is intended for immunological research and studies involving cell populations expressing this epithelial surface marker.
Background: EpCAM / CD326
EpCAM (Epithelial Cell Adhesion Molecule), also known as CD326, is a transmembrane glycoprotein involved in calcium-independent homophilic cell-to-cell adhesion. It contributes to the organization and maintenance of epithelial cell contacts.
EpCAM may also function as a growth factor receptor and is thought to participate in maintaining cells in position during proliferation. Its expression can correlate inversely with the level of E-cadherin (CD324).
EpCAM is an important molecule in tumor biology and is widely investigated in studies of epithelial cell identity, cell adhesion and cancer research.
Key Features
Applications
Flow Cytometry (FCM): Fluorescent detection and analysis of mouse EpCAM/CD326-expressing cells.
Research fields: Immunology and stem cell research.
Technical Specifications
Buffer Composition
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Usage
The suggested amount is 5 µL of antibody per test. This corresponds to approximately one million cells in a 100 µL staining volume, or per 100 µL of whole blood.
Shipping and Storage
Store at 2–8°C for up to 12 months. Protect the reagent from prolonged exposure to light and do not freeze.